O | 
| Zondag | 05/09/2021 | 14:00 | 
| Clem Scherpenheuvel - Blue Tigers | 52-60 |
B |
| Zondag | 19/09/2021 | 14:00 |
| Blue Tigers - BC Grimbergen | 42-59 |
|
| Woensdag | 29/09/2021 | 20:15 |
| Blue Tigers - GSG Aarschot | 38-53 |
|
| Zaterdag | 02/10/2021 | 18:30 |
| BC Grimbergen - Blue Tigers | 63-33 |
|
| Zaterdag | 09/10/2021 | 17:00 |
| Basket Groot Zemst - Blue Tigers | 73-40 |
|
| Zondag | 24/10/2021 | 14:00 |
| Jets Basket Zaventem - Blue Tigers | 57-51 |
|
| Zondag | 07/11/2021 | 12:00 |
| Blue Tigers - De Rode Leeuwen | 51-74 |
|
| Zaterdag | 13/11/2021 | 18:00 |
| Clem Scherpenheuvel - Blue Tigers | 75-45 |
|
| Zondag | 21/11/2021 | 12:00 |
| Blue Tigers - BBC Haacht | 52-97 |
|
| Zaterdag | 27/11/2021 | 16:30 |
| Triton Leuven - Blue Tigers | 55-48 |
|
| Zaterdag | 15/01/2022 | 16:00 |
| GSG Aarschot - Blue Tigers | 50-70 |
|
| Zondag | 23/01/2022 | 12:00 |
| Blue Tigers - BC Grimbergen | 75-53 |
|
| Zaterdag | 29/01/2022 | 18:00 |
| BC Streek Inn Vilvoorde - Blue Tigers | 64-49 |
|
| Zondag | 06/02/2022 | 12:00 |
| Blue Tigers - Basket Groot Zemst | 38-100 |
|
| Zondag | 20/02/2022 | 14:00 |
| Blue Tigers - Jets Basket Zaventem | 60-54 |
|
| Zaterdag | 26/02/2022 | 18:15 |
| De Rode Leeuwen - Blue Tigers | 62-31 |
|
| Zondag | 06/03/2022 | 12:00 |
| Blue Tigers - Clem Scherpenheuvel | 33-67 |
|
| Zondag | 13/03/2022 | 11:30 |
| BBC Haacht - Blue Tigers | 87-34 |
|
| Zondag | 27/03/2022 | 15:00 |
| Blue Tigers - Triton Leuven | 41-77 |
|
| Zondag | 03/04/2022 | 16:00 |
| BC Asse-Ternat - Blue Tigers | 0-20 (FF) |
|
| Zondag | 10/04/2022 | 12:00 |
| Blue Tigers - BC Streek Inn Vilvoorde | 48-78 |
|
| Zondag | 24/04/2022 | 14:00 |
| Blue Tigers - BC Asse-Ternat | 20-0 (FF) |
