| 
| Zaterdag | 25/09/2021 | 19:00 | 
| Basket Groot Zemst - Blue Tigers | 66-60 |
|
| Zondag | 03/10/2021 | 14:00 |
| Blue Tigers - Bavi Vilvoorde | 48-71 |
|
| Zaterdag | 09/10/2021 | 19:00 |
| BC Opwijk - Blue Tigers | 54-52 |
|
| Zondag | 17/10/2021 | 14:00 |
| Blue Tigers - Londerzeelse Dunkers | 59-55 |
|
| Zondag | 24/10/2021 | 13:00 |
| Black Devils Vorst - Blue Tigers | 39-75 |
|
| Zondag | 07/11/2021 | 14:00 |
| Blue Tigers - Bct Overijse | 71-46 |
|
| Zaterdag | 13/11/2021 | 18:00 |
| Basket Club Groot Dilbeek - Blue Tigers | 62-76 |
|
| Zondag | 21/11/2021 | 14:00 |
| Blue Tigers - Dynamo Bertem | 54-73 |
|
| Zondag | 28/11/2021 | 14:00 |
| Jets Basket Zaventem - Blue Tigers | 49-63 |
|
| Zondag | 05/12/2021 | 14:00 |
| Blue Tigers - BC Grimbergen |
|
|
| Zondag | 12/12/2021 | 16:00 |
| BC Asse-Ternat - Blue Tigers |
|
|
| Vrijdag | 17/12/2021 | 21:00 |
| GSG Aarschot - Blue Tigers |
|
|
| Zondag | 09/01/2022 | 14:00 |
| Blue Tigers - Stella Artois Leuven Bears |
|
|
| Zondag | 16/01/2022 | 14:00 |
| Blue Tigers - Basket Groot Zemst |
|
|
| Zondag | 23/01/2022 | 15:00 |
| Bavi Vilvoorde - Blue Tigers |
|
|
| Zondag | 06/02/2022 | 14:00 |
| Blue Tigers - BC Opwijk |
|
|
| Zaterdag | 12/02/2022 | 20:00 |
| Londerzeelse Dunkers - Blue Tigers |
|
|
| Zondag | 20/02/2022 | 14:00 |
| Blue Tigers - Black Devils Vorst |
|
|
| Zaterdag | 26/02/2022 | 18:30 |
| Bct Overijse - Blue Tigers |
|
|
| Zondag | 06/03/2022 | 14:00 |
| Blue Tigers - Basket Club Groot Dilbeek |
|
|
| Zondag | 27/03/2022 | 14:00 |
| Blue Tigers - Jets Basket Zaventem |
|
|
| Zaterdag | 02/04/2022 | 20:30 |
| BC Grimbergen - Blue Tigers |
|
|
| Zondag | 10/04/2022 | 14:00 |
| Blue Tigers - BC Asse-Ternat |
|
|
| Zaterdag | 16/04/2022 | 20:30 |
| Dynamo Bertem - Blue Tigers |
|
|
| Zondag | 24/04/2022 | 14:00 |
| Blue Tigers - GSG Aarschot |
|
|
| Zaterdag | 30/04/2022 | 17:00 |
| Stella Artois Leuven Bears - Blue Tigers |
|
